This keto chicken Alfredo casserole is a creamy, cheesy, low-carb chicken bake that gives you all the comfort of classic chicken Alfredo without the pasta or gluten.
It features tender chicken, spaghetti squash, a homemade keto Alfredo sauce, and a golden cheese topping that makes this casserole feel hearty and satisfying enough for the whole family.
If you've been missing creamy pasta dishes since going low-carb, this recipe is such a delicious way to enjoy those familiar Alfredo flavors while keeping things keto-friendly.
Instead of noodles, this chicken Alfredo bake uses spaghetti squash, which gives the casserole that pasta-like texture without the carb load.
It's rich, filling, and made with simple ingredients you can easily find at your local grocery store.
Plus, it's a great make-ahead dinner option for busy weeknights, meal prep, or anytime you want a low-carb casserole that feels like true comfort food.
Be sure to check out all our keto chicken recipes and keto casseroles for more easy low-carb ideas.
Why This Keto Chicken Alfredo Casserole Recipe Works
My family has always had a weakness for any recipe that features creamy Alfredo sauce. So I knew I needed to create a great recipe that used a homemade Alfredo sauce that had all the flavor they loved without all the gluten.
This keto casserole recipe works because:
- No pasta needed: Spaghetti squash gives this casserole a noodle-like texture while keeping it low in carbs and gluten-free.
- Homemade Alfredo sauce: Heavy cream, cream cheese, butter, and Parmesan create a creamy keto Alfredo sauce without flour or added starches.
- Family-friendly comfort food: This keto chicken Alfredo bake has all the creamy, cheesy flavor people love in traditional chicken Alfredo.
- Great for leftovers: You can use freshly cooked chicken or save time with leftover rotisserie chicken.
- Naturally gluten-free: Since there is no pasta or flour in the sauce, this casserole is perfect for anyone avoiding gluten.
- Easy to customize: Use chicken breast, chicken thighs, or add low-carb vegetables like broccoli or spinach.
Low-Carb Chicken Alfredo Bake With Spaghetti Squash
Traditional chicken Alfredo is usually made with pasta, which is why it can be difficult to fit into a keto lifestyle. This version keeps the same creamy flavor but swaps the noodles for spaghetti squash.
Spaghetti squash is one of my favorite low-carb pasta substitutes because once it's cooked, the flesh pulls apart into thin strands that resemble noodles. It has a mild flavor, so it allows the homemade Alfredo sauce to shine.
In this recipe, the spaghetti squash is combined with cooked chicken and a creamy Parmesan Alfredo sauce, then topped with mozzarella and more Parmesan before baking until bubbly and golden.
The result is a hearty keto chicken Alfredo casserole that is rich, satisfying, and much lower in carbs than a traditional pasta bake.
Ingredients Needed For This Alfredo Keto Casserole
Below are all the ingredients you'll need to make this chicken Alfredo keto casserole. Note that the full printable recipe card is at the bottom of the page.
For The Casserole
- Spaghetti squash
- Boneless skinless chicken breasts
- Unsalted butter
- Olive oil
- Italian seasoning
- Sea salt
- Black pepper
For The Keto Alfredo Sauce
- Heavy whipping cream
- Cream cheese
- Butter
- Parmesan cheese
- Garlic powder
- Onion powder
- Nutmeg
- Sea salt
- Black pepper
For The Cheese Topping
- Mozzarella cheese
- Parmesan cheese
- Fresh parsley for garnish
How To Make Chicken Alfredo Bake
You'll begin by first cooking your spaghetti squash. There are several ways you can cook spaghetti squash. Your options vary from oven, microwave, and even instant pot.
Once the spaghetti squash is cooked and cool enough to handle, use a fork to scrape the flesh into strands.
If the squash releases a lot of moisture, let the strands sit for a few minutes and gently blot them with paper towels. This extra step helps keep the casserole creamy instead of watery.
Next, season the chicken and cook it in a large skillet with butter and olive oil until it is golden and fully cooked. Cut the chicken into bite-sized pieces so every serving gets plenty of chicken throughout the casserole.
While the chicken cooks, prepare the keto Alfredo sauce. Melt the butter in a saucepan over medium-low heat, then add the heavy cream, cream cheese, seasonings, and Parmesan cheese.
Stir until the cheese melts and the sauce becomes smooth and creamy.
Add the cooked spaghetti squash and chicken to a large bowl, then pour the Alfredo sauce over the top. Toss everything together until the squash and chicken are fully coated in that rich sauce.
Transfer the mixture to a buttered baking dish, then top it with mozzarella and Parmesan cheese.
Bake until the casserole is hot, bubbly, and golden brown on top. If you want extra color, broil it for a few minutes at the end, keeping a close eye on it so the cheese does not burn.
Garnish with fresh parsley and serve warm.
How To Cook Spaghetti Squash For This Casserole
There are a few easy ways to cook spaghetti squash for this low-carb chicken Alfredo casserole.
Oven Method
Cut the spaghetti squash in half lengthwise and remove the seeds. Place the squash cut side down on a parchment-lined baking sheet and bake until tender. Once it is cool enough to handle, use a fork to scrape out the strands.
Microwave Method
Slice the squash in half, remove the seeds, and microwave until tender. You can also cook the squash whole after piercing it several times, then slice it open once it has softened.
Would you like to save this?
We'll email this post to you, so you can come back to it later!
Instant Pot Method
Cut the squash in half, remove the seeds, and pressure cook until tender. Once cooked, scrape the inside with a fork to create the strands.
Tips For The Best Chicken Alfredo Bake Without Pasta
The biggest tip for making a great spaghetti squash casserole is to avoid excess moisture. Spaghetti squash can release water after cooking, and too much moisture can thin the Alfredo sauce.
After scraping the cooked squash into strands, let it sit for a few minutes. If needed, gently press the strands with paper towels to remove extra liquid before adding them to the casserole.
Another tip is to use freshly grated Parmesan if possible. It melts better into the sauce and gives the Alfredo a smoother texture. Pre-shredded cheese can still work, but freshly grated cheese gives the sauce a richer finish.
For the chicken, you can use boneless skinless chicken breasts, chicken thighs, or leftover rotisserie chicken. Rotisserie chicken is a great shortcut when you want to make this an easy keto chicken casserole on a busy night.
Can I Use Rotisserie Chicken?
Yes, rotisserie chicken works beautifully in this keto chicken Alfredo casserole. It saves time and makes this recipe even easier.
Simply shred or chop the cooked chicken and fold it into the spaghetti squash with the Alfredo sauce.
Since the chicken is already cooked, you can skip the pan-searing step and go straight to assembling the casserole.
Just be sure to use plain or simply seasoned rotisserie chicken so it does not compete with the Alfredo sauce.
Can I Add Broccoli?
Yes, broccoli is a great addition to this low-carb chicken Alfredo bake. It pairs well with the creamy sauce and adds more texture to the casserole.
Use lightly steamed broccoli and drain it well before adding it to the casserole. You do not want to add raw broccoli because it may not cook evenly, and frozen broccoli should be thawed and dried first so it does not water down the sauce.
Is Chicken Alfredo Keto?
Traditional chicken Alfredo is usually not keto-friendly because it is served over pasta. The Alfredo sauce itself can often be low in carbs when made without flour, but the noodles are where the carbs add up quickly.
This keto chicken Alfredo casserole keeps the creamy sauce and chicken but replaces pasta with spaghetti squash. That simple swap makes it a much better fit for a low-carb or keto lifestyle.
Storage & Serving Tips
Store leftovers in an airtight container in the refrigerator for up to three days. Reheat individual portions in the microwave or warm the casserole in the oven until heated through.
Because this recipe uses a cream-based Alfredo sauce, I do not recommend freezing it. Cream sauces can separate once thawed, which changes the texture of the casserole.
Serve this keto chicken Alfredo bake with a simple green salad, roasted broccoli, sautéed spinach, or your favorite low-carb vegetable side.
What Is Spaghetti Squash?
If you are not familiar with spaghetti squash, it's a winter squash that gets its name from the long spaghetti-like strands that form when the cooked vegetable flesh is scraped with a fork.
The gluten-free community has been using it for years as a pasta alternative.
Once the cooked squash flesh is pulled apart with a fork, it has the perfect consistency of pasta. It has a stringy texture that mimics its high-carb counterpart beautifully.
And since it has a very mild taste, it really fools your taste buds. It's no wonder it's also known as "noodle squash."
Other Keto Chicken Casserole Recipes To Try
The following are some more keto chicken casserole recipes you may want to try soon.
- Keto chicken Florentine casserole
- Keto chicken enchilada cauliflower rice casserole
- Keto chicken kiev casserole
- Keto king ranch chicken casserole
- Keto creamy spinach chicken casserole
- Keto BBQ chicken casserole
- Keto chicken divan casserole
- Keto chicken carbonara casserole
- Keto chicken lasagna
- Keto Mexican chicken casserole
- Keto chicken taco casserole
- Keto chicken cornbread casserole
- Keto chicken parmesan casserole
Tag Us
I sure hope you'll give this recipe a try. When you do, be sure to tag us on Instagram and Facebook. It truly encourages me to keep sharing and perfecting these keto recipes for you.
You can also visit our Amazon Store for some of our favorite keto baking tools, pantry staples, and low-carb recommendations.
Grab Our Books & Recipe App
In case you don't know, we've authored two keto cookbooks, Essential Keto Bread and Essential Keto Desserts, both inspired by your requests over the years.
You can also find even more easy keto recipes for breakfast, lunch, dinner, snacks, and desserts inside the Fit to Serve Group App on iOS and Android.
Join Our Jesus And Keto Movement
Looking for support on your keto journey? We invite you to join our private Jesus and Keto Facebook group, where we encourage one another to pursue lasting transformation through faith, grace, and a low-carb lifestyle.
Be sure to also request our FREE Jesus and Keto E-Book: First 7 Days. We pray it blesses you.
Keto Chicken Alfredo Casserole (Gluten-Free)
This keto chicken Alfredo casserole is sure to silence your pasta cravings. Boneless, skinless chicken breasts and spaghetti squash come together for an authentic-tasting keto alfredo chicken bake. Enjoy all the flavors of this classic Italian dish without worrying about consuming too many carbs or gluten.
Ingredients
- 1 large spaghetti squash, about 3.5 pounds
- 2 tablespoons of unsalted butter
- 3 cups of heavy cream
- 2 ounces of softened cream cheese
- 1 ½ teaspoons of sea salt, divided
- ½ teaspoon garlic powder
- ½ teaspoon onion powder
- ⅛ teaspoon of nutmeg powder
- 1 ¼ teaspoon of freshly cracked black pepper, divided
- 1 cup of shredded Parmesan cheese
- 1 ½ pounds of chicken breasts cut into 1-inch cubes
- 1 teaspoon of salt free Italian seasoning
- 1 tablespoon of olive oil, to cook the chicken
Cheese Topping
- 2 cups of shredded mozzarella cheese
- 1 cup of shredded Parmesan cheese
Garnish
- ¼ cup of fresh parsley chopped, for garnish
Instructions
- Cut the chicken into 1-inch cubes and season with ½ teaspoon of salt, ¼ teaspoon of black pepper, and Italian seasoning. Pan-sear the chicken in a large skillet with two tablespoons of butter and olive oil on your stovetop over medium-high heat. Cook the chicken until it is golden and fully cooked or reaches an internal temperature of 160 degrees F. Set it aside.
- Preheat the oven to 400 degrees if cooking the squash in the oven.
- Line a large baking tray with parchment paper to cook the spaghetti squash, and set it aside.
- Grease a 13X9-inch baking dish with butter for the casserole.
Spaghetti Squash Prep
1. Cut the ends of the spaghetti squash and cut the squash lengthwise.
2. Place each half of the spaghetti squash facedown onto the prepared baking tray. Bake the squash in the 400-degree preheated oven for 45-50 minutes or until a knife inserted into the squash enters easily.
3. Flip the squash to the cut side and using a fork remove the seeds, then proceed to rake the squash with your fork to remove the spaghetti strands from the squash. This should happen easily. If not return the squash back into the oven and cook for another 10-15 minutes. If ready turn off the oven.
4. Once the squash is fully cooked and the spaghetti-like strands can be removed easily from the skin of the squash allow the squash to cool for about 15 minutes before removing scraping all the flesh of the squash.
5. Place all the spaghetti squash strands into a large bowl. Set it aside.
6. Proceed to make the keto alfredo sauce.
Keto Alfredo Sauce
- In a small saucepan, melt the butter over low heat.
- To the melted butter, add the heavy cream, garlic powder, onion powder, salt, pepper, nutmeg powder, softened cream cheese, and shredded parmesan cheese.
- Cook the sauce over medium-low heat for about 5-7 minutes until the cheeses melt and the sauce thickens. Set it aside
Cheese Topping
- In a small bowl, combine the shredded mozzarella cheese and shredded parmesan cheese. Top the casserole before baking.
Assembling The Alfredo Chicken Casserole
- Preheat the oven to 350 degrees.
- In a large bowl, add the spaghetti squash, the cooked chicken pieces, and the alfredo sauce, and toss well. Stir well, making sure that everything is coated well with the sauce.
- Spread the chicken squash mixture evenly into the buttered casserole dish.
- Top evenly with the cheese topping.
- Bake the casserole for 35-45 minutes until golden brown.
- Broil for 3-5 minutes if, at the 45-minute mark, the casserole hasn't browned.
- Store leftovers in the refrigerator for up to 3 days.
Notes
Ways To Cook Spaghetti Squash
- Microwave instructions: Slice the squash in half lengthwise, remove the seeds, and microwave for about 15 minutes. Scrape the flesh for spaghetti strands. You could also microwave whole after poking the flesh all over and microwaving for about 25-30 minutes, turning the squash halfway through the cooking process.
- Instant Pot instructions: Slice the squash in half lengthwise, remove the seeds, and pressure cook for 7-8 minutes. Scrape the flesh for spaghetti strands.
- Oven instructions: To bake in the oven. Slice the squash in half, remove the seeds, place the squash face-down on a baking sheet, and roast at 400 degrees for about 40-45 minutes. Then, proceed to scrape the flesh for spaghetti strands.
For a fun presentation, rather than placing the prepared Chicken Alfredo into a casserole dish, you could alternatively place it into the squash shells and then place the spaghetti squash boats in a large casserole dish or rimmed baking sheet before baking.
Store any leftovers in an airtight container in the refrigerator for up 3 days. Due to the cream sauce, I do not recommend freezing this casserole. I find that the sauce tends to separate once it thaws.
Rotisserie Chicken Option
You can save time an effort by using leftover rotisserie chicken and therefore skip the cooking of the chicken step.
Nutrition Information:
Yield:
10Serving Size:
1Amount Per Serving: Calories: 325Total Fat: 21.8gSaturated Fat: 14.1gCholesterol: 95mgSodium: 480mgCarbohydrates: 9.5gNet Carbohydrates: 7.6gFiber: 1.9gSugar: .1gProtein: 5.4g
Leave a Reply